Book Hotels in San Luis, AZ

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top San Luis hotels

La Fuente Inn & Suites

La Fuente Inn & Suites

3 out of 5
1513 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Sep 18 to Sep 19
$105 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Breakfast was great and we were lucky to find a space right next to the gate entrance that we could back in, because we had bikes on the back. They were really safe and secure."

Reviewed on Sep 11, 2026

Opens in a new windowLa Fuente Inn & Suites
Radisson Hotel Yuma

Radisson Hotel Yuma

3.5 out of 5
1501 S Redondo Center Drive Yuma AZ
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $145 total per night from Sep 13 to Sep 14
$145 total
Sep 13 - Sep 14
Total with taxes and fees
2 hot tubs, an outdoor pool, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, ...
"Great central location with clean and comfortable rooms. Nice bar for night cap and great coffee to start the day with. The staff was very attentive, polite and friendly. We enjoyed the included breakfast. It's our go to place when we are in town."

Reviewed on Sep 11, 2026

Opens in a new windowRadisson Hotel Yuma
Extended Stay America Premier Suites - Yuma

Extended Stay America Premier Suites - Yuma

2.5 out of 5
550 South Rio Vista Dr Yuma AZ
$78 nightly
The price is $86 total per night from Sep 21 to Sep 22
$86 total
Sep 21 - Sep 22
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public ...
"The location was clean and looked fairly new. The room was comfortable and had everything we needed. Would stay again"

Reviewed on Sep 11, 2026

Opens in a new windowExtended Stay America Premier Suites - Yuma
Best Western Yuma Mall Hotel & Suites

Best Western Yuma Mall Hotel & Suites

3 out of 5
1450 S Castle Dome Ave Yuma AZ
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $90 total per night from Sep 14 to Sep 15
$90 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Everyone was helpful specially the cooking staff they we're awesome."

Reviewed on Sep 11, 2026

Opens in a new windowBest Western Yuma Mall Hotel & Suites
Motel 6 Yuma, AZ - East

Motel 6 Yuma, AZ - East

2 out of 5
1445 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$35 nightly
The price is $38 total per night from Sep 27 to Sep 28
$38 total
Sep 27 - Sep 28
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A terrace and a snack bar/deli are also ...
"they stated that they have queen size beds. They do not have queen size beds. This is a full-size bed. They had no soap no extra toilet paper half a roll. The it was clean but the entrance to our room the grass was overgrown dog poop all over you couldn’t walk you have to go all the way around to ..."

Reviewed on Sep 12, 2026

Opens in a new windowMotel 6 Yuma, AZ - East
Days Inn by Wyndham Yuma

Days Inn by Wyndham Yuma

2 out of 5
1671 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Sep 17 to Sep 18
$74 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Our room was clean and thank God the air was on because it was a hot day"

Reviewed on Sep 8, 2026

Opens in a new windowDays Inn by Wyndham Yuma
Yuma Inn & Suites

Yuma Inn & Suites

2.5 out of 5
1550 S Castle Dome Ave Yuma AZ
Fully refundable
$66 nightly
The price is $73 total per night from Sep 15 to Sep 16
$73 total
Sep 15 - Sep 16
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Unfortunately, this place has run down and used and abused, and not properly maintained. Wallpaper was filling off the walls holes in the wall carpets dirty, and filthy ice. Machines didn’t work on any of the floors. Everything was outdated. It seemed like there was still logos and advertisements ..."

Reviewed on Sep 9, 2026

Opens in a new windowYuma Inn & Suites
Wingate by Wyndham Yuma

Wingate by Wyndham Yuma

3 out of 5
1760 Sunridge Dr Yuma AZ
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $115 total per night from Sep 13 to Sep 14
$115 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Opens in a new windowWingate by Wyndham Yuma
Everhome Suites Yuma East I-8 by Choice Hotels

Everhome Suites Yuma East I-8 by Choice Hotels

3 out of 5
2011 East 18th Street Yuma AZ
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $149 total per night from Sep 27 to Sep 28
$149 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Free self parking, laundry facilities, ...
Opens in a new windowEverhome Suites Yuma East I-8 by Choice Hotels
Don't see what you're looking for?
See all available properties in San Luis
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in San Luis?
Family trips are where you make the best memories, but traveling with youngsters can be difficult. These kid-friendly San Luis hotels come with perks that aim to keep young and old alike relaxed and happy: Unpack your bags at Pet-Friendly San Luis Abode ~ 22 Miles to Yuma!. It comes with a travel crib, a firepit and a knack for making families feel welcome. Also look into Little Casita, Big Comfort! Minutes from the border.. It comes with internet access, clothes washing facilities and ample opportunities to hang out together.
Where can I find cheap hotels in San Luis?
At Travelocity you'll find really nice hotels in San Luis at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near San Luis rather than in San Luis. We may find you even better rates, too.
How do I find the best San Luis hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in San Luis then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in San Luis?
The cheapest hotel in San Luis is $38. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in San Luis?
There are 271 hotels in San Luis on Travelocity.
What are the best hotels in San Luis?
San Luis has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in San Luis for you!
When is the best time to visit San Luis?
If you want the joy of a fun-filled trip in peak season, visit San Luis during January, February and March. If you'd prefer the peace of off-season, book a stay during quieter months, such as June, July and December.
When is the cheapest time to stay in San Luis?
Based on historic data is usually the cheapest month to visit San Luis. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in San Luis?
There are multiple hotels in San Luis that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to San Luis. We have plenty of kid-friendly hotels in San Luis to choose from on Travelocity!
Why book a hotel in San Luis through Travelocity?
Because we have the top hotels in San Luis! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in San Luis on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent San Luis hotel reviews by fellow wanderers

La Fuente Inn & Suites

La Fuente Inn & Suites

5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"Breakfast was great and we were lucky to find a space right next to the gate entrance that we could back in, because we had bikes on the back. They were really safe and secure."
A verified traveler stayed at La Fuente Inn & Suites
La Fuente Inn & Suites

Explore More Ways to Travel with Travelocity